What are SARMs?
SARMS offer the benefits of Anabolic Steroids but they do not cause the harsh side effects.
This quality makes them extremely desirable and intriguing to any class of patient wanting assistance in building muscle mass, increasing strength or dropping fat.
The word SARM stands for “Selective Androgen Receptor Modulator,” and just like the other selective receptor modulators, SARMS can either block, or stimulate, the same nuclear hormone receptors under different conditions. Consequently, if it can block or stimulate a receptor in a tissue selective manner, it may be able to mimic the beneficial effects in one tissue, and, at the same time, minimize the unwanted effects of the synthetic steroidal hormones in other tissues. Since SARMS are a class of androgens (a specific class of hormones that serve as ligands), they can bind to cellular androgen receptors. As a result, the androgen receptors will trigger a complex signal transduction pathway that will lead to a greater expression of specific genes.
In fact, anabolic androgenic steroids (AAS) and prohormones also bind to the androgen receptors, resulting in muscle growth. However, SARMS possess full anabolic activity in muscle and bone, yet they have a minimal effect on the prostate as opposed to AAS, which can be very harmful to this gland. As an additional advantage, SARMS are orally available and require no injections. In spite of being oral compounds, SARMS are not methylated, so they are not liver toxic.
Due to the fact that SARMS are very specific to the androgen receptors, they can be extremely useful for safe muscle building in patients. All in all, SARMS have an abundance of qualities; they are highly beneficial to bones, muscle tissues, and sexual function without the conversion of androgens into estrogens seen with steroids or prohormones.
